Normal folic acid metabolism in iron-deficient rats
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چکیده
منابع مشابه
Normal folic acid metabolism in iron-deficient rats.
I . Weanling rats were fed on an iron-deficient diet without added folic acid and litter-mate controls received the same diet supplemented with Fe. Groups of deficient and control animals were killed at intervals of up to 88 days and glutamate formiminotransferase activity in liver and folic acid activity in liver and serum were measured. 2. No differences were found between the results from th...
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I . The effects of ingestion of diets deficient in both copper and iron on storage of these elements and on the red cell indices have been studied in rats. 2. Injection of Cu into rats whose stores of Cu had been virtually exhausted resulted in a temporary increase in the concentration of plasma Fe and depletion of the Fe stored in the liver. Storage of Fe in the spleen seemed to be affected so...
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The amidine carbon atom (C-Z) of L-histidine is known to be an efficient metabolic precursor of single carbon units. Following the administration of n-histidine-2-Cr4, the radioactivity has been found in CO2 and urea, in carbons 2 and 8 of purines, in the hydroxymethyl group of serine, and in choline, and creatine (l-4). The major pathway of histidine degradation which involves deamination to u...
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Iron absorption studies with oral 59FeSO4 2.2% respectively) . Compared with the were performed on 13 iron-depleted, 1 1 normal controls, iron was decreased in iron-loaded, and 10 control rats, and nonthe epithelial cells of the iron-defIcient heme iron was determined in both isogroup, whereas higher concentrations lated epithelial cells and defoliated muwere observed in the defoliated mucosa c...
متن کاملTHE RELATIONSHIP BETWEEN ALUMINIUM TOXICITY AND IRON METABOLISM IN RATS
The relationship between aluminium toxicity and iron metabolism was studied. Male rats were exposed to aluminium by daily intraperitoneal injection of 40pmolelkg body weight. After 45 days, aluminium intoxified rats had a significant loweredserum ferritin (55%), iron (42%), TIBC (25%) and hemoglobin(31%). At thesame time the serum ceruloplasmin level was elevated by 60%. This result shows t...
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ژورنال
عنوان ژورنال: British Journal of Nutrition
سال: 1969
ISSN: 0007-1145,1475-2662
DOI: 10.1079/bjn19690074